Synthetic embryology: controlling geometry to model early mammalian development

Methods in Mammalian Embryology

This is the first volume in a series designed to provide a continuing overview of new experimental procedures and concepts in the field of endocrinology. The editors have gathered a distinguished group of contributors, and some topics, such as "Basic Concepts of Saturation Analysis Techniques" by R. P. Ekins and "Endocrinological Implications of Prostaglandins" by J. D. Flack, P. Ramwell, and J...

Human embryonic stem cells: an in vitro model to study mechanisms controlling pluripotency in early mammalian development.

The property of pluripotency confers the capacity for differentiation into a large number of cell types including extra-embryonic, somatic and germinal cells. During normal development, pluripotency is acquired by the cells of the early embryo, which shortly thereafter undergo differentiation, whereas embryonic stem cells (ESCs) uniquely maintain pluripotency while undergoing extensive in vitro...

Synthetic Cevian Geometry Synthetic Cevian Geometry 1

Early Embryology of the Chick

aTlhe first edlition of this book appeared in 1920. I uised the tllir(l edition as an undergraduate studenlt in an embryology course in 1946. As a student I found the book to be excellent. In the laboratory portion of the course I found tlle il-lulstrations to be a perfect guide as I studied the living dleveloping chick embryo. Nearly all of the illustrations were drawn by Dr. Patten from direc...

Mechanisms controlling early development of the liver

Over the last decade significant advances have been made in our understanding of the molecular mechanisms that control early aspects of mammalian liver development. Studies using tissue explant cultures and molecular biology techniques as well as the analysis of transgenic and knockout mice have identified signaling molecules and transcription factors that are necessary for the onset of hepatog...